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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a7a8fac9ceadf2067311277d1bca3c36f345fbbe2c2c16d96980c775e3a9563f' 
  AND token = 'quLHucAz0mEI2SZE+QyuBQehS5hgrqp48jwd0A8Ei3o=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}