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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ad0f7522b2d94b54d1641230f007e08c6aa533bac6a39af4eb409c2361f5071d' 
  AND token = 'z2/7c4CesJugoyeOjJSstqMYrOW1jnHW8bsIVSw0G9Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}