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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6e9d6032f4660f0d33e7c76d4761b3653bafee6b87e06bb74852365cea3b6078' 
  AND token = 'uZvePJmf+3f0vrcwZIoRwBFggcNGD62xAAYohRAH2HE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}