SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5b1a7c3a7b81c609fac88aad8328f0d8e4a82550ce20e472b71a49d30e220953' 
  AND token = '00qQIRuoKPoVdCFc7Xrr4R33Z3LAPg1rtzz6guuBtL0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}