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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ff72c2f4c06b83deb8284b990cf8c4c68405b9eb0d69c35e0f90d71c722b4e05' 
  AND token = 'J1c6m3AYd3/ZKs6ejXppY0jcR3Ygy+9aRyTB897UobM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}