SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'de94b64826d33335b8fcf424616ce3126f5994a1c2193b0980adb414e7a6a765' 
  AND token = 'CBhylAD2RiimOpLAkZoIDnIG8GtsUAdb6fsHnAdLkK0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}