SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e84243f576e6d3f75b7c0e026e83922849ae535ebf3625de5e7dd2ebdad1f489' 
  AND token = 'inzndfVD5+SpjLqSb6zuHw7KJV2c1X9fX2hfTFRvCUI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}