SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '10df56f2db36906a667b65a5f20675330f7f25763b35f1269fa15f6a854945a6' 
  AND token = 'CnzH8CIis23zCalp2xNxrMQv9PDI7x8kOaNOxMMlzDw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}