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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7b453734f553de5e44afa226d3ec8ae3ae3499c24df5233fac8c5f27d5ba5963' 
  AND token = 'qvJI0Qz9VJEMbJ22my9S5rL0Yh6MZIeXVN9Cze/E0K4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}