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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '462e40b11137433ae57e1b38a282d542e636e6d2cd58a17d527cc8ac1bc47d6a' 
  AND token = '8YEbWL03gxzGmjeECXXOAf/MD2vUVsigYvXqn0LiMKw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}