SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '000d7a636be68c0aec227a05fd57cf5c81a22536c991318dbf53ae1cbe00c8d2' 
  AND token = 'plQL861DtZ9U93mN37iz8ct5BCgxV0Ujc3dARWR77Hs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}