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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '416b9b527e31bb306fedeb24cb4437ffad3cfc398f54bac26e5be6ee93b24b56' 
  AND token = '1N1A/n9TBIrJm86wpCG2YSg8ClVngjgnw2D+0loYpdE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}