SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f1a10955e2d6bba08c32210e54a135f9b54a319c0b6b005c3c9abfd27c0bcc82' 
  AND token = '5zLnX6rQbnWF+vtGHwGb4G6MwVobJsUT0gNX1XGmRmE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}