SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a5888728f5da045300cbd46eefed81bae62a03f386ba4374350d7d585229876f' 
  AND token = 'VJnz3p2mI37LM9ShivL18JHMCKeNW+XViLi9HHjrrLQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}