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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e76e95dba67621cef6af471add492fd478b02c4ef501e4cc020b1bbf2f1a63e9' 
  AND token = '7BTOJmTURZzq968MWiwqy3j2JDsGOg3X1QHW5OUHXiM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}