SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f65ef86c79b7a08f68325b00b9aa7b37835a14946d41c8d0af3fc3793f082c27' 
  AND token = 'ywfqp0t4SKXXVidQertwVw78/lcZJAOkP/r5xGssbqA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00044

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}