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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9e0901bbd4b20d56f365df0577df850a14db4cc6fbe518a35c511d8cde8df6d0' 
  AND token = 'm1a7veAfCc8WI7o0X0/oMjRyRtrPADxge/026Bic8mc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}