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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5378bd280ec82d38ce4d0767969b614523c590b745b92e9fa20999d501023fc6' 
  AND token = '0ARXGmOB2CGuOhYuV+bcACGoIquSVnJ2dBaR3W7bjy0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}