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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cdd94a69816118b3979e931d4e80afc1fd0bc9ff43af054158977c0625323ede' 
  AND token = 'j7LgZHZsdOTVL1Zw4nc0hrO9mm6smrG+KD8h4QTggiM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}