SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4613de5070583924efdb52e4d24dd7f05d1056ef9813112e3fc71390adbcd439' 
  AND token = 'ceoeBtnsuc0Wk0c8b/HrWeDj8M5LHykgbL7JRNRzlg8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}