SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7a5eca5569ac165ee727756602da02b46cabdc646a3cf4fc767247e72e664916' 
  AND token = 'aiNJkvJRE73GCatBFF0uv1TVaXsgx0gBIZkShoOSrK8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}