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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f6aad79a668beee1189c84181e2865fbbc072eb4666bd93e29057b0162ad0159' 
  AND token = 'OYKvseTyM4HZkF72A/G51v1sfQARUNWHwprWhMlqBEE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}