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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3000c94aa8ddf24d130b8c871bf35504c6bf2b38575fd5cdaae4d91850a3b03a' 
  AND token = '0GPmjCe8B6iuyPeoEC44zQ9BhK0VbfuKWF7R856HaQ8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}