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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '45e67acace1eedbd4630ac0be92bc200cff934bd0948e9cab87f8f1db370a71c' 
  AND token = 'Zy6FLmtH7jsT5C5n/aTEe4FlZu68Iw1ZXNm/Gw9CO58=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}