SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '42426e5579889a4ffd6bbe665ca71e67e96e8c9ca132b47571f2c168d78ebaca' 
  AND token = 't6xgwRZInZ8MspT8IJFNBSPCSmZyHCox0F93VgKu6ag=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}