SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ade6f16a80efe5dce980bbf935cb2c7ba35347255e76a6ec97ce1ad5401ee635' 
  AND token = 'N+ikL66bHDXSoDd5jHMn8lkMe/7Z4hCLQOphElnvHAM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}