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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9a1186265b5d4bc618d8a44f92bc040bdd0807f14b07a399fa245edbaa10eac6' 
  AND token = 'yFvt8eYXWx90135/e4fR4U0p7Y4tVTU2X13Bg/ShvgE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}