SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5e1c7ab92538023701851f28318d5682a63e6245fa5bdfe3f99c62da67b79b0c' 
  AND token = '+F8NZN4uQzv+SJ8JNpNySgX8vAF5PGDnr5Hd3v+kraI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}