SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3d141ef0bbd1bc484629c464d32c822cbc8fce82824c403aaa116b9987e022b9' 
  AND token = '57Qgl4Xc4RF5yAmY42+Hm1FbnZc10pjX3GYjJIr7Ds0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}