SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0c0f8e29bec59657f5f250b687b6ede72a77331e8c7242b35a05270fa6346578' 
  AND token = 'sOF12p0E32sE0Y4f+02mUYvRbTzMPLwrJqpxsbamooc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}