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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5839496e9376ea980b0b0871dba372fc91fd6c8b48ab4498d49fd0f589af4cd8' 
  AND token = 'b4bE9WuyB2C9OI2an57/C5nw0PxGmdlg5VnBPvI/Dow=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}