SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e8ff2e7e7b0e02b02237bdf059a009081f07a499366668e870a8f5cb26cc8283' 
  AND token = 'MxXrR7hgH3q8Q41kfzDhoE0mBbN1TjVJ/cU1uNVE1xw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}