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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '848d13c7a96bed5fcc2a2c06313d2c339b9af3efb879124d7992c5f2fbab6fd8' 
  AND token = '9UYr7PpL5m8cdwe2FRjrQS1q4cLRfF0cHf1vE0DpujQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}