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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1279e29c43ea541f19bb3cb3b8893bb701cb8007347149e8d0f5be52d56ef58f' 
  AND token = 'ugBhPOEJc4hq7R0vKWcH6BLWFoQQeLynPtPLqzyM84Q=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}