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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4e330b397b84c784419b0f6dc08ceaf4dad25978f95cf5ffdcee7d8028e39c71' 
  AND token = 'T1cvxOnp7034bgTbLcHNQUij76hriQ25XhvnRcYPKNA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}