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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6c6ca46a41e50935b26257ace5aecf2ba6aaefc8a3c5734b5f807431fc0fa4fc' 
  AND token = '3rBy7BFXYdZypEpo65od297/mq47+HpjNSFoD1ikh1s=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}