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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '420d3b57cfa2c6b5ebd811abb8a54e993a482b7d03a465fe5e7a3e4efd3e8a04' 
  AND token = 'EH4pWqTVPBkBULK6kpvW9uLXyMWU7UtWs40IJ8IB078=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}