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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '69bf2728a338233c57854a2ec06e52c7711e734dc01ff3e5e883985dfbd3748c' 
  AND token = '9E1I2VU6H9TvkWaqIYed3G+BGp2wV+iDYGgp2o/Ml6Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}