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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '52478689cd9a0c290c56986ce26badfda4953b273ce425afc80bd0d07cfae14b' 
  AND token = 'dNKhUkb7VOmfflIXq5m2PrwH8gPGgl1xKNd/k3YxuQ4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00013

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}