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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7366a4424d361492c3535b5d478a4cb508527538e38de803bba3ba5afa6abf0d' 
  AND token = 'j3PL8vVJ1kNWY7odHOI+1a/xtPDLYTylWIPwVqLGSyw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}