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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '125fc0e39e65da7799f154021f49dd86e165c997298d584c96c66d35ce5d62a4' 
  AND token = 'OY8T9i8c3n1dvCMwMUK+ZvKIXtTpZ687qnRGClRNNtc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}