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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5753c8a53b3e04a5fa94f6a6f3f6a97d5ef58cb35727c8fec84b6aa352e91af7' 
  AND token = 'Hq3csOVp702pF0th9iozpRNN0RyRsV8CHMY5u6lBUjA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}