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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cfe5cd7449fd439e1c87507d8e465ba495c1fa02ad88b86d0b0b1ea62971dc58' 
  AND token = 'SPfzlO4ytfW/6Vq8XXMu9eDvhMM+0BQl4mXG73TVDhg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}