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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8611ee1dcdfd11e81e55053eb26675ccefd822302db2be460fe31da5c9dea476' 
  AND token = 'PtZKwFW9uJ1l/nXo39wQ+r9U0Ond5mNkbCyb7mtY9PA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}