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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '26a0d2dcac777b4881b487f1042f6306903910e77c050d53b472e1968a135339' 
  AND token = 'FCNlXRZjnw4wKHDFPKoW/2YTsA7eviNK4fFf3ybC5Pk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}