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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3684a1b50073d3aa7aea05df8dd2cc374df54856f789fa4f10b6d9528d9722f7' 
  AND token = 'CZuO+E+t5XnwZWHI47tDL5r/PkAJafjQ7lqIuRycQqo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}