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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '73ad9e3b4994e6d361e3bf9ad1fa365125a70bfdc745e99af8d4907ff37c5df6' 
  AND token = 'tc75i19Gh3+FNKdSxuwZSHBW59yyEsZr/hnQ6V1NGj4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}