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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '04a0075ba1a050a6d16ee4334c91d0516e9e7e4bbe6dd29e355e623492ae3b0f' 
  AND token = 'CSEn2s5h/X6rfK5jTw6UXusmRPwMq6SCR9VVX4fiMJA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}