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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e980c86a0511ae2088144fe10105f8dd2f506d34a108015c2afa79ff44d0d225' 
  AND token = 'U/26LTzBRujNz5JlGNAUBqE5aSeZM/37sHORyoRRa8k=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}