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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'daf2457957be89257bae3387f4e1e51b6cdb77dbd5474958bc1e7e5173587218' 
  AND token = 'NBhnEh49fFzvpu3BdHAciHGSx/2vShHjlhO0pswUpNA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}